
Today on Drug Discovery & Development
From data to drug candidates: Optimizing informatics for ML and GenAI
Machine learning (ML) has become a cornerstone of modern drug discovery. Today, many companies are taking ML developments a step further using generative AI (GenAI) to search for molecules under specific constraints, such as solubility and patent status, and to optimize for desired properties like potential therapeutic success. In doing so, GenAI can enhance the efficiency, speed…How Thermo Fisher’s KingFisher PlasmidPro crunches hours of plasmid prep to 5 minutes hands-on
Five minutes of hands-on bench time now separates researchers from purified plasmid DNA using a new automated system from Thermo Fisher Scientific. The company’s cartridge-based KingFisher PlasmidPro automates the traditionally hours-long maxi-prep process. The KingFisher PlasmidPro benchtop instrument offers walk-away operation. Kevin Lowitz, vice president and general manager for sample prep at Thermo Fisher Scientific,…Drug Discovery and Development See More >

How a ‘rising tide’ of inclusivity is transforming clinical trials
Let’s say there’s a Black female patient with an aggressive form of breast cancer. She meets with her oncologist to discuss a promising targeted therapy that recently won FDA approval. The drug showed strong efficacy in clinical trials, with a 65% response rate. Yet when she asks about efficacy data specific to Black women, she…
Mary Marcus appointed CEO of NewAge Industries

Biotech in 2025: Precision medicine, smarter investments, and more emphasis on RWD in clinical trials

External comparator studies: What researchers need to know to minimize bias

Tiny breaths, big impacts: Bridging the gap between laboratory discoveries and clinical applications in breath research with mouse models
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Spatial biology: Transforming our understanding of cellular environments
Spatial biology is revolutionizing our understanding of how cells interact with their natural environments. Although that may sound like an overstatement, it isn’t. Spatial biology involves the use of advanced imaging and molecular techniques to visualize and map the location of cells, transcripts, proteins and their interactions within tissues. Traditional biological studies have long focused…

Biotech in 2025: Precision medicine, smarter investments, and more emphasis on RWD in clinical trials

Genomics in 2025: How $500 whole genome sequencing could democratize genomic data

St. Jude pioneers gene editing and structural biology to advance pediatric research
![A display of DNA sequencing output from an automated ABI 373 sequencer. [National Human Genome Research Institute (NHGRI)]](https://www.drugdiscoverytrends.com/wp-content/uploads/2024/06/51187236177_b7b566a401_k-268x170.jpg)
Helix and Recursion join forces in quest to crack the AI-driven drug discovery code
Infectious Disease See More >

Pregnancy associated with less long COVID: Researchers call for studies on protective biology
A recent study published this week, on April 1, 2025, found that pregnant women with SARS-CoV-2 infection may have a lower risk of developing long COVID compared to non-pregnant women. This finding, detailed in Nature Communications, shed light on pregnancy’s protective effects. The large-scale retrospective study, conducted under the guidance of researchers from Weill Cornell…

How technology advances are helping scientists unlock the mysteries of zoonotic diseases

Advances in next generation vaccine development for SARS-CoV-2

World AIDS Day Summit & Celebration slated for early December

Moderna and Pfizer win approval for KP.2 vaccine as KP.3 variants account for about half of current cases
Oncology See More >

AP Biosciences charts course for safer CD137 bispecifics with its T-cube platform
AP Biosciences is building the protocol around one key objective: confirm that conditional CD137 agonism, a tumor-restricted T-cell costimulation, can be delivered safely in patients whose HER2-positive solid tumors express the p95HER2 variant, a truncated, drug-resistant form of HER2. To that end, it recently dosed the first patient in the Phase 1/2 trial of its…

Cellares and UW-Madison partner to automate manufacturing for novel solid tumor CAR-T

Why smaller, simpler molecular glues are gaining attention in drug discovery

COTA Healthcare announces AI milestone in real-world oncology data
