
Today on Drug Discovery & Development
How Sheba Medical Center became OpenAI’s first international hospital partner
OpenAI’s first international hospital partnership is taking shape at a giant medical center where English is not the default language and where the electronic health record does not come from Epic, the dominant U.S. EHR vendor. That institution is Sheba Medical Center, the Israel-based medical center with its own 50-plus-person AI Center within ARC, its…FDA issues final PDUFA meeting guidance, expands use of written responses
The FDA has finalized new guidelines for meetings between the FDA and sponsors or applicants relating to the development and review of drugs or biological products under the Prescription Drug User Fee Act (PDUFA). The FDA first published the draft guidance on Sept. 22, 2023, when it collected public comment on the guidelines. The final guidelines contain several changes from the draft, including modifying when INTERACT…Drug Discovery and Development See More >

As 59% fewer pharma companies cut staff in Q2 in 2026, job postings rise 15%
2022 was a big year for layoffs in biopharma. So were the next three. Novartis, for instance, outlined plans to cut up to 8,000 jobs in 2022, after pharmaceutical industry job cuts jumped 280% in 2021. Biogen followed in 2023 with a “Fit for Growth” program that put roughly 1,000 roles on the block. Bristol…

Sai Life Sciences’ bet on information-dense scale-up and how it is responding to pharma clients who want acceleration

Ahead of PharmSci 360, DigiM CEO on turning hidden microstructures into drug-release predictions

CEO of CDMO AustinPx on its exclusive agreement with Thermo Fisher’s Patheon division

Top pharma companies set sustainability goals, but emissions are still increasing
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Genomics/Proteomics See More >

New cell imaging method reveals hidden enzyme activity
Negative biosensors have often been unusable because, as the sensors lose signal when activity is detected, regions of high enzyme activity can look identical to regions with no activity. Researchers at the University of Illinois Chicago have solved this problem with a new cell imaging method that allows scientists to see previously hidden enzyme activities by flipping the optical readout of…

Beyond the silver bullet: Why precision medicine is the next frontier for the $1 trillion obesity market

Columbia-CZ team develops 10.3M parameter model that outperforms 100M parameter rivals on cell type classification

Spatial biology: Transforming our understanding of cellular environments

Biotech in 2025: Precision medicine, smarter investments, and more emphasis on RWD in clinical trials
Infectious Disease See More >

As measles cases hit a 35-year high, Trump executive order backs a narrower childhood vaccine list
The U.S. entered August with more measles cases so far this year than it recorded during all of 2025. With kindergarten MMR coverage down to 92.5% from 95.2% before the pandemic, and Stanford modeling published in JAMA projecting measles could become endemic again within roughly two decades at current rates, President Donald Trump issued a…
Oncology See More >

As chemo overtreatment comes into focus, Atossa bets on tamoxifen’s active form
As evidence mounts that some hormone receptor-positive, HER2-negative breast cancer patients are being overtreated with chemotherapy, researchers are working to identify which patients can safely avoid it, and to expand the treatment options available to those who can. Atossa Therapeutics thinks endoxifen, the active metabolite behind tamoxifen, could be an important addition to that toolkit. …

How ConcertAI turned CancerLinQ into a point-of-care oncology intelligence platform

Moderna bets on mRNA’s second act with cancer, autoimmune programs and AI research platform

Calderasib’s real innovation: designed for combinability and potency




























