OcuMedic said today that it entered into an exclusive supply agreement and picked up a strategic investment from Gelest for its proprietary drug-eluting soft contact lens of an undisclosed amount. Under the terms of the agreement, Morrisville, Pa.-based Gelest is set to manufacture and supply OcuMedic’s key chemistry components used in the controlled release of…
Intersect ENT’s Ascend study misses endpoint
Intersect ENT (NSDQ:XENT) shares plunged today after the company said it failed to meet the primary endpoint in a study of its Ascend investigational drug-coated sinus balloon. The 70-person, randomized, double-blind trial was designed to compared treatment with Intersect ENT’s DCB when randomized against an uncoated balloon control. The study missed the primary endpoint, frontal sinus…
FDA clears Insulet’s OmniPod Dash as insulin pump alternative
Insulet (NSDQ:PODD) said today that it won FDA clearance to market its Omnipod Dash alternate controller-enabled (ACE) infusion pump as an integrated insulin pump. The Acton, Mass.-based company received FDA 510(k) clearance for the Omnipod Dash in June 2018 and launched the device earlier this year. The latest indication states that the pump can reliably and…
Enhanced Human Blood-Brain Barrier Chip Performs in Vivo-Like Drug and Antibody Transport
Like airport security barriers that either clear authorized travelers or block unauthorized travelers and their luggage from accessing central operation areas, the blood-brain-barrier (BBB) tightly controls the transport of essential nutrients and energy metabolites into the brain and staves off unwanted substances circulating in the blood stream. Importantly, it’s highly organized structure of thin blood…
Female Cannabis Users Underrepresented in Health Research, Study Reveals
Polysubstance Use, Social Factors Associated With Opioid Overdose Deaths
A new study led by Boston Medical Center’s Grayken Center for Addiction shows that opioid-related overdose deaths involving another substance is now the norm, not the exception, in Massachusetts. The researchers analyzed opioid overdose death data from the Massachusetts Department of Public Health, which showed that 82 percent of those deaths involved an opioid and…
Chemists One Step Closer to Opioid Alternative
New Method Simplifies the Search For Protein Receptor Complexes, Speeding Drug Development
For a drug to intervene in cells or entire organs that are not behaving normally it must first bind to specific protein receptors in the cell membranes. Receptors can change their molecular structure in a multitude of ways during binding – and only the right structure will “unlock” the drug’s therapeutic effect. Now, a new…
Research Reveals Insulin-Producing Beta Cells May Change Function in Diabetes
Immune System Discovery Could Aid Quest for Stem Cell Therapies
Novel Study Discovers ‘Metabolic Fingerprint’ to Help Treat, Diagnosis and Prevent Cervical Cancer
Inflammatory Bowel Disease During Childhood Linked to Higher Cancer Rates and Early Death
Does Insulin Resistance Cause Fibromyalgia?
Study Links Gene to Sleep Problems in Autism
Up to 80 percent of children with autism spectrum disorder (ASD) experience sleep problems. The source of these problems has been as much of a mystery as the exact causes of ASD, which scientists are still working to unravel. A new study led by a team of neuroscientists at Washington State University has brought scientists…
Drug Treats Type 2 Diabetes in Children, Team Announces
Novel Therapies Slow CKD Progression in Patients With Diabetes
Spinal Muscular Atrophy Drug May Help Kids With Later-Onset Disease
Researchers Learn How ‘Bad Cholesterol’ Enters Artery Walls
Stroke Patients Receive Different Amounts of Physical Therapy
Blood Thinner Found to Significantly Reduce Subsequent Heart Failure Risks
Scientists Translate Brain Signals into Speech Sounds
Study Highlights Anti-Tumor Activity of Curcumin on Stomach Cancer
In Mice, Eliminating Damaged Mitochondria Alleviates Chronic Inflammatory Disease
Inflammation is a balanced physiological response — the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and chronic diseases. To help keep tabs on inflammation, immune cells employ a molecular machine called the NLRP3 inflammasome. NLRP3 is inactive in a healthy cell, but…
