[Coronavirus image courtesy of CDC]
Janssen and the virology lab led by Dr. Dan Barouch at BIDMC have started preclinical testing of multiple vaccine prospects, with the goal of identifying a COVID-19 vaccine candidate for clinical trials by the end of the month. A Phase 1 clinical study of the potential vaccine candidate could start by the end of the year.
Janssen is already preparing to upscale production and manufacturing capacities to meet global needs once the vaccine is available.
“It is critical to work with the best scientific minds as we look to rapidly identify and develop solutions to the COVID-19 outbreak,” said Dr. Paul Stoffels, executive committee vice chair and chief scientific officer at Johnson & Johnson.
“We are grateful for talented and experienced collaboration partners like Dan Barouch and his team at BIDMC. By mobilizing our collective resources, we believe we can leverage the top science and cutting-edge capabilities to respond to this pandemic,” Stoffels said in a news release.
Janssen’s coronavirus vaccine development will utilize the company’s AdVac and PER.C6 technologies to rapidly upscale production of an optimal vaccine candidate, according to the company. The company has already used the technology to develop its investigational Ebola (which also utilizes its MVA-BN technology), Zika, RSV and HIV vaccines.
The Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center worked closely with Janssen on developing the Zika and HIV vaccines.
“We are currently evaluating a series of potential vaccine candidates for COVID-19,” Barouch said. “This collaboration with Janssen is aimed at the development of a COVID-19 vaccine that would allow for rapid development, large-scale manufacturing, and global delivery.”
Johnson & Johnson’s Janssen has already been collaborating on COVID-19 vaccine development with the Biomedical Advanced Research and Development Authority (BARDA), part of the Office of the Assistant Secretary for Preparedness and Response (ASPR) at the U.S. Department of Health & Human Services.
Janssen is also screening its library of antiviral molecules to accelerate the discovery of potential COVID-19 treatments and provide relief for people around the world.
For more information on Johnson & Johnson’s multipronged response to identifying critical solutions to the COVID-19 outbreak, please visit: www.jnj.com/coronavirus.
Filed Under: Drug Discovery, Drug Discovery and Development, Infectious Disease
Excellent progress to save humankind all over the world from the deadly attack of COVID-19, Coronavirus attack. Hats off to Johnson & Johnson and all its partners in their noble work to save the sufferings of humanity.
Hi
If this virus comes from bats, as they say, has it ever been observed, studied their environment to know what means they have to counter it, to cure it?
Best regards
Why did it take so long, several months, from identifying the vaccine candidate to start a phase 1 clinical trial?