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Drug Discovery and Development

Pharma 50: The 50 largest pharmaceutical companies in the world

Our editorial team gathered the most recent data on annual revenue, R&D spend, employee numbers, leadership and more. The pharma giants can be found in a diverse group of countries, including the U.S., China, European Union, Japan, India, U.K. and more.

Check out our related features as we update them for 2021 and new features as they become available:

And click through the 2020 listings and learn essential information about the companies powering the global pharmaceutical industry (2021 listings are being posted periodically):

RankCompanyHeadquarters2020 Revenues ($USD)
1Sinopharm (pharmaceutical distribution segment)China$50,446,739,666
2Roche Pharmaceuticals (division of Roche Group)Switzerland$49,516,455,427
3NovartisSwitzerland$48,659,000,000
4MerckUSA$47,994,000,000
5AbbVieUSA$45,804,000,000
6Janssen (Johnson & Johnson’s pharmaceutical segment)USA$45,572,000,000
7GSKU.K.$43,537,603,200
8Bristol Myers SquibbUSA$42,518,000,000
9PfizerUSA$41,908,000,000
10SanofiFrance$41,086,740,000
11Takeda PharmaceuticalJapan$29,948,845,895
12AstraZenecaU.K.$26,617,000,000
13Gilead SciencesUSA$24,689,000,000
14Eli LillyUSA$24,539,800,000
15AmgenUSA$24,240,000,000
16Bayer (Pharmaceuticals Division)Germany$19,657,020,000
17Novo NordiskDenmark$19,410,703,364
18Boehringer IngelheimGermany$17,163,157,895
19Teva PharmaceuticalIsrael$16,659,000,000
20Merck KGaA, Darmstadt, GermanyGermany$16,149,714,000
21BiogenUSA$13,444,600,000
22ViatrisUSA$11,946,000,000
23Astellas PharmaJapan$11,701,891,740
24Daiichi SankyoJapan$9,014,010,114
25Otsuka Holdings (pharmaceutical business)Japan$8,945,495,411
26CSL, including CSL BehringAustralia$8,796,600,000
27Regeneron PharmaceuticalsUSA$8,497,100,000
28Bausch HealthCanada$8,027,000,000
29Chugai Pharmaceutical (Roche, majority owner)Japan$7,369,357,558
30EisaiJapan$6,514,525,192
32UCBBelgium$6,095,580,000
33GrifolsSpain$6,087,643,320
34Alexion PharmaceuticalsUSA$6,070,000,000
35ServierFrance$5,344,320,000
36Sumitomo Dainippon PharmaJapan$4,521,371,043
37Sun Pharmaceutical IndustriesIndia$4,514,904,235
38Abbott (Established Pharmaceutical Products)USA$4,303,000,000
39MenariniItaly$4,275,000,000
40Jiangsu Hengrui Medicine Co.China$4,017,120,014
41Sino BiopharmaceuticalChina$3,418,209,206
42ShionogiJapan$3,122,035,962
43Aurobindo PharmaIndia$3,115,402,823
44CatalentUSA$3,094,300,000
45IpsenFrance$3,062,268,000
46Endo InternationalIreland$2,903,074,000
47H. LundbeckDenmark$2,702,140,673
48IncyteUSA$2,666,702,000
49Jazz PharmaceuticalsIreland$2,363,567,000
50Dr. Reddy’s LaboratoriesIndia$2,354,911,934

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