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NIH starts Phase 3 trial of blood clotting treatments for COVID-19

By Chris Newmarker | March 8, 2021

COVID-19 coronavirus

[Photo by Fusion Medical Animation on Unsplash]

The NIH announced today that it has launched the last of three Phase 3 clinical trials to evaluate blood thinners to prevent life-threatening blood clots in adults with COVID-19.

As part of the  Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) initiative, the trial will study the use of Bristol Myers Squibb/Pfizer’s Eliquis blood thinner in patients discharged from the hospital following a case of moderate-to-severe COVID-19. The other two ACTIV studies involve hospitalized and nonhospitalized COVID-19 adults.

The trials are taking place at more than 100 sites worldwide.

Researchers noticed early in the COVID-19 pandemic that many people who died have blood clots throughout their bodies — clotting that can cause multiple health complications ranging from organ damage to heart attack. The ACTIV-4 trials are meant to answer critical questions about properly use blood thinners or anticoagulants to treat COVID-19 cases.

 


Filed Under: clinical trials, Drug Discovery, Infectious Disease
Tagged With: anticoagulants, Bristol-Myers Squibb, clinical trials, coronavirus, covid-19, Eliquis, NIH, Pfizer
 

About The Author

Chris Newmarker

Chris Newmarker is the executive editor of WTWH Media life science's news websites and publications including MassDevice, Medical Design & Outsourcing and more. A professional journalist of 18 years, he is a veteran of UBM (now Informa) and The Associated Press whose career has taken him from Ohio to Virginia, New Jersey and, most recently, Minnesota. He’s covered a wide variety of subjects, but his focus over the past decade has been business and technology. He holds bachelor’s degrees in journalism and political science from Ohio State University. Connect with him on LinkedIn or email at cnewmarker@wtwhmedia.com.

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