How a Small Molecule Halts the Spread of a Toxic Protein Associated with Alzheimer’s Progression
Drug Shows Promise for Treating Alcoholism
UCLA researchers have found that an anti-inflammatory drug primarily used in Japan to treat asthma could help people overcome alcoholism. Their study is the first to evaluate the drug, ibudilast, as a treatment for alcoholism. Study participants were given either the drug (20 milligrams for two days and 50 milligrams for the next four) or…
New Tuberculosis Therapy Could Be More Potent Than Current Treatments
Taking a new approach toward tuberculosis therapy, a UCLA-led research team has devised a potential drug regimen that could cut the treatment time by up to 75 percent, while simultaneously reducing the risk that patients could develop drug-resistant TB. To identify the regimen, the researchers launched a systematic search for an optimal drug treatment using…
Study Links Autism to Changes in Micro-RNAs
Scientists at UCLA have found that the brains of people with autism spectrum disorders show distinctive changes in the levels of tiny regulator molecules known as microRNAs, which control the activities of large gene networks. The study is the first to demonstrate the broad importance of microRNAs in autism disorders. The researchers found evidence that…
Cancer Spreading: Caught in The Act
Cancer-Fighting Therapy Shows Promise as Wound-Healing Treatment
A type of targeted therapy that has shown promising results treating advanced melanoma could also be used to help speed up how the skin repairs itself from injury, UCLA researchers have found, providing a potential new way to accelerate healing of acute and chronic wounds. In the United States alone, chronic wounds affect more than 6.5…
Viral Therapy Shows Promise for Treating Advanced Brain Cancer
A team of scientists, led by doctors at UCLA, has successfully demonstrated that a modified virus can extend the lives of people with recurrent glioblastoma, the most common and aggressive form of brain cancer. In a phase I multi-center clinical trial, the researchers found that of the 43 participants who were given the investigational treatment…