
Chemists Unveil Versatile Method for Making Chiral Drug Molecules
Chemists at The Scripps Research Institute (TSRI) have invented a new technique for constructing chiral drug molecules. Chiral molecules are those whose structural complexity allows them to have mirror-image, “left-handed” and “right-handed” forms. For drug molecules, usually only one of those forms works—the other may even have unwanted side-effects—and thus pharmaceutical chemists have a great…
New Method Could Turbocharge Drug Discovery, Protein Research
A team led by scientists at The Scripps Research Institute (TSRI) has developed a versatile new method that should enhance the discovery of new drugs and the study of proteins. The new method enables researchers to quickly find small molecules that bind to hundreds of thousands of proteins in their native cellular environment. Such molecules,…