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Air-dryable master mixes replace lyophilization in the manufacturing of molecular assays

By Brian Buntz | February 25, 2021

master mixes

These master mixes can be air-dried in a straightforward process. Image courtesy of Meridian Life Science.

Quantitative PCR (qPCR) is the mainstream molecular technology for in vitro diagnostic assays. The introduction of freeze-drying to create ambient-temperature stable qPCR tests has improved assay stability and consistency and has enabled diagnostic companies to reduce supply chain and shipping costs. However, lyophilization is a complex and expensive process that requires expertise and sophisticated equipment and, consequently, has become a barrier to entry into the ambient-temperature stable assay market. Air-drying is an alternative technology that is less expensive, easier to perform and easily adopted in-house, enabling diagnostic manufacturers to create temperature stable molecular assays.

Get the full story from our sister site, Pharmaceutical Processing World. 

 


Filed Under: Drug Discovery and Development, Infectious Disease
Tagged With: air-dryable master mixes, covid-19, lyophilization, Meridian Bioscience, Meridian Life Science, qPCR, Quantitative PCR
 

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