A network meta-analysis (NMA), a method for comparing multiple therapies within a single analysis, uses direct and indirect evidence within a network of randomized controlled studies. An NMA is a type of meta-analysis, which itself is a research technique used to statistically analyze the findings of independent studies. An NMA is thus a meta-analysis comparing…
Why emergency authorization of COVID-19 therapies could pose regulatory questions
Few of the COVID-19 therapies in use in the U.S. have won full FDA approval. The widespread use of emergency use authorization may accelerate the distribution of disease-modifying agents and vaccines to patients, but it also could cause regulatory complications. “I’m nervous about the prospect of there never being a COVID vaccine that meets the…