After establishing her lab at Cornell in 2019 and achieving notable success with publications in top journals, Liz Kellogg, Ph.D., associate member in the department of Structural Biology at St. Jude Children’s Research Hospital received a unique opportunity. St. Jude Children’s Research Hospital had embarked on a major expansion of its structural biology and genome…
Caribou Biosciences’ CEO discusses CRISPR progress, future goals, and gender equality in biotech
Founded in 2011, Caribou Biosciences is a pioneer in the development of CRISPR genome editing technologies, a field honored with the Nobel Prize in Chemistry in 2020. Co-founded by Jennifer Doudna, Ph.D., one of the Nobel laureates, and CEO Rachel Haurwitz, and two other CRISPR pioneers, the company has raised over $800 million in funding,…
Viral vector analysis for successful targeting in gene therapy
April 25, 2023 is an important anniversary in the field of genomics. It marks the seventieth anniversary of four scientists — James Watson, Francis Crick, Maurice Wilkins, and Rosalind Franklin — publishing a paper in Nature and proposing the double helix structure of DNA1. The discovery of the double helix with complementary strands helped scientists…
GenScript debuts single- and double-strand DNA service for cell and gene therapy development
The popularity of CRISPR-based non-viral gene insertion techniques is fueling interest in CRISPR/Cas genome-editing technology that uses the homology-directed repair (HDR) pathway to insert DNA sequences. To respond to that demand, biotech services firm GenScript has introduced GMP-compliant single-stranded DNA (ssDNA) and closed-end linear double-stranded DNA (dsDNA) services. The company’s GenExact ssDNA services support up to…
ERS Genomics and ZeClinics team up on gene-edited zebrafish disease models
The zebrafish, commonly found in aquariums, is widely tapped in drug development to understand disease mechanisms. The advent of CRISPR gene editing has given researchers more flexibility in developing disease models, thanks to its ability to create gene-edited zebrafish variants. To that end, the privately-held company ZeClinics (Barcelona) is using CRISPR-based techniques to make unique…