The popularity of CRISPR-based non-viral gene insertion techniques is fueling interest in CRISPR/Cas genome-editing technology that uses the homology-directed repair (HDR) pathway to insert DNA sequences. To respond to that demand, biotech services firm GenScript has introduced GMP-compliant single-stranded DNA (ssDNA) and closed-end linear double-stranded DNA (dsDNA) services. The company’s GenExact ssDNA services support up to…

The zebrafish, commonly found in aquariums, is widely tapped in drug development to understand disease mechanisms. The advent of CRISPR gene editing has given researchers more flexibility in developing disease models, thanks to its ability to create gene-edited zebrafish variants. To that end, the privately-held company ZeClinics (Barcelona) is using CRISPR-based techniques to make unique…