Guava Technologies, Inc. released information on their recent advancements that describe an experimental methodology and the new Guava Simplicity Analysis Software which exploit the advantages of plate-based flow technology. These technological improvements result in an overall process that can expedite the drug discovery process by providing a means for extraction of key findings from the complex data sets encountered with functional screening of siRNA knockdown assays.
The Guava EasyCyte Plus System, with integrated Guava Simplicity Software, provides a platform for secondary target validation and compound screening. Guava Technologies’ flow cytometers overcome the limitations of inference-based measurements of transfection efficiency and protein knockdown through direct quantitative analysis of populations at the single cell level, according to the company. The Simplicity Analysis Software’s intuitive architecture and ease of use facilitates the process of asking biological questions on multi-dimensional data sets through visualization of user-defined parameters in the form of heat-maps. Comparative results are displayed at the experiment level rather than on an individual well/sample basis.
Published in Drug Discovery & Development magazine: Vol. 11, No. 12, December, 2008, p.7.
Filed Under: Drug Discovery