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Drug Discovery and Development

Mindset Pharma collaborates with psychiatric research hospital to study psilocybin-like compound

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MindsetMindset Pharma Inc. (CSE:MSET; FSE:9DF; OTCQB:MSSTF) has announced its intent to work with the Toronto-based Centre for Addiction and Mental Health (CAMH) on a preclinical study related to its lead asset, MSP-1014, a patented second-generation psilocybin-like compound. 

The company plans on exploring the use of the serotonin 2A receptor agonist MSP-1014 as a treatment for anxiety and depressive disorders. 

Mindset plans on testing MSP-1014 alongside psilocybin.

In the preclinical study involving rats, Mindset and CAMH will explore how macro and micro doses of psychedelic compounds affect expression levels of molecular biomarkers of brain plasticity. 

Dr. Anh Dzung Lê, Senior Scientist and Head of Neurobiology of Alcohol Lab in the Campbell Family Mental Health Research Institute at CAMH, will lead the study. Dr. Douglas Funk, a project scientist in the CAMH Neurobiology of Alcohol Lab will offer support. 

“Mindset’s drug discovery platform is built on a broad spectrum of high-quality scientific data generated in preclinical models. This collaboration will profile and build our understanding of the observed superiority of our lead asset, MSP-1014, to psilocybin at the molecular level. We are excited to partner with Dr Lê and Dr. Funk who are pioneers in mental health research to build this dataset and continue in our shared mission to advance groundbreaking new treatments to patients who are waiting.” said James Lanthier, CEO of Mindset, in a statement. “This study is the beginning of a strong partnership with CAMH, and we are excited for the research to come.”

Filed Under: Psychiatric/psychotropic drugs
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About The Author

Brian Buntz

As the pharma and biotech editor at WTWH Media, Brian has almost two decades of experience in B2B media, with a focus on healthcare and technology. While he has long maintained a keen interest in AI, more recently Brian has made making data analysis a central focus, and is exploring tools ranging from NLP and clustering to predictive analytics.

Throughout his 18-year tenure, Brian has covered an array of life science topics, including clinical trials, medical devices, and drug discovery and development. Prior to WTWH, he held the title of content director at Informa, where he focused on topics such as connected devices, cybersecurity, AI and Industry 4.0. A dedicated decade at UBM saw Brian providing in-depth coverage of the medical device sector. Engage with Brian on LinkedIn or drop him an email at bbuntz@wtwhmedia.com.

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