JEOL USA announced the introduction of the company’s first commercially available MALDI-TOF mass spectrometer, the JEOL JMS-S3000 SpiralTOF. The SpiralTOF reinvents Time-of-Flight ion optics with an extended flight length in a compact footprint, delivering a resolving power of greater than 60,000 (FWHM) over a wide mass range of m/z 10-30,000 – the highest resolving power of all commercial MALDI-TOF systems.
JEOL’s patented technology consists of a staggered figure-8 ion trajectory of 17 meters. By refocusing the ion packets during each turn, the divergence of the ions is reduced over the flight distance. The SpiralTOF ion optical system is engineered to overcome the limits of delayed extraction with kinetic energy convergence resulting in high sensitivity, resolving power and mass accuracy (less than 1ppm) over a wide mass range.
To meet the diverse needs of researchers, the SpiralTOF is available in four configurations:
• MALDI-TOF MS with unsurpassed high mass resolving power and high mass accuracy.
• Linear TOF option for high sensitivity analysis of high molecular weight samples and/or those that undergo post-source decay
• TOF/TOF option for acquiring high energy collision-induced dissociation (CID) product ion spectra of monoisotopically selected precursor ions
• TOF/TOF plus Linear TOF for full analytical capability
With the addition of the SpiralTOF to its mass spectrometer product line, JEOL makes available a unique analytical instrument for proteomics, synthetic polymers, materials, and biomolecules.
JEOL offers a full suite of mass spectrometry systems: the first commercially-available open air ion source, Direct Analysis in Real Time (DART), paired with its AccuTOFTM-DART Time-of-Flight mass spectrometer; the GC-TOF AccuTOF-GCv mass spectrometer; the JEOL MStation double focusing magnetic sector mass spectrometer; and the GCMate II benchtop GC/MS. Additionally, a family of 300 to 930MHz NMR spectrometers completes its chemical analysis product line.
Filed Under: Drug Discovery