Millipore expanded its PI3 kinase line and now offers 17 lipid kinases, available both for purchase and as part of its KinaseProfiler service. Lipid kinases are one of the most promising new classes of potential drug targets. PI3 kinases regulate a wide variety of cellular functions, including cell growth, proliferation, differentiation, motility, survival, and intracellular trafficking. As a result, defects in PI3 kinase function lead to multiple disease states, including several forms of cancer.
Combined with Millipore’s PI3 Kinase HTRF Assay, KinaseProfiler service, and small-molecule inhibitors, the expanded lipid kinase panel provides researchers with the most complete solution to studying lipid kinase signaling. The new lipid kinase panel includes both wild type and disease-linked mutants.
This article was published in Drug Discovery & Development magazine: Vol. 11, No. 1, January, 2008, pp. 41.
Filed Under: Drug Discovery