Drug Discovery and Development

  • Home Drug Discovery and Development
  • Drug Discovery
  • Genomics/Proteomics
  • Oncology
  • Neurological Disease
  • Infectious Disease
  • Orphan Drugs
  • R&D 100 Awards

Are Women Really Under-represented in Clinical Trials?

By Wiley | January 12, 2018

Several studies have reported a lack of gender diversity in clinical trials, with trials including mostly adult males; however, a recent review of publicly available registration data of clinical trials at the US Food and Drug Administration for the most frequently prescribed drug classes found no evidence of any systemic significant under-representation of women. The findings are published in the British Journal of Clinical Pharmacology.

The analysis entailed 38 drugs with a total inclusion of 185,479 trial participants and revealed that through the clinical development phase, the proportion of women participating in trials gradually increases from 22% in phase 1 to over 48% for phase 2/3 trials.

“The results of this investigation show that drug trials are appropriately designed regarding inclusion of men and women. Furthermore, the underrepresentation of women in trials as observed in the 1980s and before seems to be resolved for most drug trials that we investigated,” said co-author Dr. Robert Rissmann, of the Centre for Human Drug Research, in The Netherlands. “Although some earlier studies had reported an underrepresentation of women, our results are fully in line with recent results of a Cochrane meta-analysis, which underlines the robustness of our findings.”

Read the full study here. 

Related Articles Read More >

RCSB Protein Data Bank now has more than 1,000 SARS-CoV-2 proteins
Data sciencea
Q&A: Keys to unlock data science potential for drug discovery
Ivermectin not supported for mild COVID-19, study says
Emulate Bio
Organ-chips could streamline drug development, but hurdles remain

DeviceTalks Tuesdays

DeviceTalks Tuesdays

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.

Need Drug Discovery news in a minute?

We Deliver!
Drug Discovery & Development Enewsletters get you caught up on all the mission critical news you need. Sign up today.
Enews Signup

R&D Twitter

Tweets by @RandDWorld
Drug Discovery and Development
  • Enews Signup
  • Contact Us
  • R&D World
  • Pharmaceutical Processing
  • Drug Delivery Business News

Copyright © 2021 WTWH Media LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media
Privacy Policy | Advertising | About Us

Search Drug Discovery

  • Home Drug Discovery and Development
  • Drug Discovery
  • Genomics/Proteomics
  • Oncology
  • Neurological Disease
  • Infectious Disease
  • Orphan Drugs
  • R&D 100 Awards