Malvern Instruments has extended the applications for its Viscotek Triple Detector Array (TDA), the multi-detector platform for gel permeation/size exclusion chromatography (GPC/SEC), through the inclusion of a new viscometer in the setup. The TDA maximises the productivity of GPC/SEC analysis by simultaneously measuring absolute molecular weight, molecular size and intrinsic viscosity. The new viscometer combines unrivalled sensitivity with an innovative 316 stainless steel transducer construction that offers excellent chemical resistance. It therefore provides the most precise intrinsic viscosity and structural information for an expanded range of biomolecules, natural and synthetic polymers.
The unique viscometer design uses digital inert transducer technology to give a faster, more sensitive response to viscosity changes than traditional transducers. Its 316 stainless steel construction means that there are now few limitations, in terms of salt content or pH, on the chromatographic conditions that can be used. This is a significant benefit for protein analysis. The use of inert capillaries in the measuring flow path is also advantageous for many biomolecule applications.
The TDA lies at the heart of the Viscotek TDAmax: a complete, advanced GPC/SEC system suitable for all macromolecular applications. However, each element of the TDA can be purchased alone or in combination, offering exceptional flexibility to those with existing GPC/SEC systems. UV and/or PDA detectors are also available to further augment detection capabilities. These are especially useful for the analysis of composition for copolymers and/or conjugated proteins.
Date: April 27, 2010
Source: Malvern Instruments
Filed Under: Drug Discovery