The maXis from Bruker Daltonics is an Electrospray Ultra-High Resolution tandem TOF (UHR-Qq-TOF) mass spectrometer for applications including small molecule identification, metabolomics, quantitative proteomics, as well as biomarker discovery and validation.
The maXis offers ultra-high resolution of 40,000 – 60,000 FWHM over a broad mass range, MS and MS/MS mass accuracy typically between 600 and 800 ppb, at speeds of up to 20 full spectra per second. It also offers 20 Hz full spectra acquisition at ultra-high mass resolution for high-speed liquid chromatography; novel IonCooler technology delivers excellent MS/MS sensitivity over a broad m/z range; high dynamic range of five orders of magnitude for trace detection in complex mixtures; sub-ppm mass accuracy in both MS and MS/MS mode for high confidence IDs; and SmartFormula 3D unambiguous determination of molecular sum formulae for molecules up to 1 kDalton.
“Now ultra-high resolution mass spectrometry over broad mass ranges is finally compatible with ultra performance liquid chromatography,” explained Bruker Daltonics Executive Vice President Dr. Ian Sanders. “Our new maXis indeed represents a major step forward in tandem mass spectrometry, offering a no-compromise solution for exceptional accurate mass, ultra-high resolution over a broad mass range and high sensitivity MS and MS/MS analysis at a speed able to take full advantage of modern, fast liquid chromatography or fast capillary electrophoresis separations.”
Filed Under: Drug Discovery
