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Takeda plans to acquire GammaDelta for its solid tumor drug pipeline

The companies have been collaborators since 2017.

By Brian Buntz | October 27, 2021

Takeda/GammaDeltaTakeda Pharmaceutical Company Ltd. (TSE:4502/NYSE:TAK) is moving forward with its plan to acquire its collaborator GammaDelta Therapeutics Ltd. (London).

The acquisition is subject to customary closing conditions. Takeda projects that the deal will close in the first quarter of its fiscal year, which will end on June 30, 2022.

The acquisition would bolster Takeda’s immuno-oncology and immunotherapy portfolio. GammaDelta has experience working with gamma delta (γδ) T cells as potential therapies for solid tumors hematological malignancies.

GammaDelta had developed allogeneic variable delta 1 (Vδ1) gamma-delta (γδ) T cell therapy platforms. Those platforms encompass blood-derived and tissue-derived cells.

“We’re committed to developing cell therapies that will have an impact on large segments of patients by focusing on off-the-shelf, allogeneic cell therapies that are highly accessible and have the potential to address solid tumors,” Christopher Arendt, head of oncology cell therapy and therapeutic area unit of Takeda said in a statement.

Arendt went on to say that γδ T-cell therapy platforms “represent a differentiated approach to target both solid tumors and hematological malignancies.”

The company’s allogenic blood-derived GDX012 variable δ1 and γδ T-cell platform is the most mature in its pipeline.

Earlier this year, GammaDelta announced that FDA had authorized an investigational new drug application as a potential treatment for hematological malignancies.

FDA also granted orphan drug designation to allogeneic Vδ1 γδ T cell therapy (GDX012) to treat acute myeloid leukemia.

Takeda and GammaDelta Therapeutics have been working together since 2017. GammaDelta was founded in 2016.


Filed Under: Oncology
Tagged With: gamma-delta, GammaDelta Therapeutics, immuno-oncology, immunotherapy, oncology, T cell therapy platforms, Takeda Pharmaceutical Co
 

About The Author

Brian Buntz

As the pharma and biotech editor at WTWH Media, Brian has almost two decades of experience in B2B media, with a focus on healthcare and technology. While he has long maintained a keen interest in AI, more recently Brian has made making data analysis a central focus, and is exploring tools ranging from NLP and clustering to predictive analytics.

Throughout his 18-year tenure, Brian has covered an array of life science topics, including clinical trials, medical devices, and drug discovery and development. Prior to WTWH, he held the title of content director at Informa, where he focused on topics such as connected devices, cybersecurity, AI and Industry 4.0. A dedicated decade at UBM saw Brian providing in-depth coverage of the medical device sector. Engage with Brian on LinkedIn or drop him an email at bbuntz@wtwhmedia.com.

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