Engineers at MIT designed a new way to trigger cells that could lead to targeted therapies for cancer and other diseases. Using an RNA sensor for the trigger, the researchers ensure that synthetic genes activate only in specific cells. They demonstrated that the sensor could accurately identify cells expressing a mutated version of the p53…
This T-cell vaccine could be the future of COVID-19 protection
The current mRNA vaccines from Moderna (Nasdaq:MRNA) and Pfizer (NYSE:PFE)/BioNTech (Nasdaq:BNTX) stimulate the production of neutralizing antibodies that bind to the spike protein of SARS-CoV-2. But there is a novel mRNA vaccine that activates T cells to attack cells infected with the virus. Developed by researchers at MIT and other institutions, the new vaccine could…
MIT researchers come up with new strategy to create a potential antibiotic
Researchers at MIT are touting a novel method to synthesize a natural compound that has shown potential as an antibiotic. The chemists produced himastatin using the synthesis method and also managed to generate variants of the molecule, some of which showed antimicrobial activity, according to a news story from the university’s website. The compound appears…
New AI out of MIT predicts how proteins will attach
MIT researchers are touting a machine learning model that can predict the complex that will form when proteins bind together. The technique represents an improvement on speed by somewhere between 80 and 500 times faster than state-of-the-art software methods and often predicts protein structures that are closer to actual structures that have been observed experimentally…
MIT, Indian researchers grow tiny brains in 3D-printed bioreactor
Scientists in Cambridge, Mass. and Chennai, India, are touting self-organizing brain tissue growth in a 3D-printed system. Published results in Biomicrofluidics highlight the work of the Massachusetts Institute of Technology (MIT) and Indian Institute of Technology Madras scientists, who have grown small amounts of the self-organizing brain tissue, known as organoids, in a tiny 3D-printed system that…
MIT researchers tout new machine learning technique for assessing drug molecules
MIT researchers are touting a new machine-learning technique called DeepBAR that can quickly calculate the binding affinities between drug candidates and their targets. DeepBAR produces precise calculations in a fraction of the time compared to conventional techniques, according to the researchers. They think the software could potentially accelerate drug discovery and protein engineering. “Our method…
Study tests proven blood clot buster against COVID-19
While vaccines and pharmaceutical treatments for COVID-19 might be far off, researchers at the Massachusetts Institute of Technology and University of Colorado are exploring a stopgap measure that could buy time for critically ill patients, according to a release by the two institutions. In a clinical trial being planned for hospitals in Massachusetts and Colorado,…