computational biology

Generative artificial intelligence (GAI) has captivated the world, and for good reason. Platforms like ChatGPT have demonstrated capabilities that gave the general public a deeper understanding of AI’s capabilities. AI, too, is showing potential in drug discovery. From designing novel drug molecules to predicting protein structures, AI is offering a new path forward, potentially accelerating…

Digital pathology is disrupting the drug development process, replacing traditional microscopy rooted in Victorian Era approaches with high-resolution images and AI-powered analysis tools. In a recent editorial webinar, industry experts Nathan Buchbinder (chief strategy officer at Proscia), Dr. John Cochran (chief medical officer and chief pathologist at Q² Solutions, an IQVIA subsidiary), and Dr. Monika…

In a packed panel discussion at GTC, moderated by NVIDIA Founder and CEO Jensen Huang, the architects of the groundbreaking transformer model gathered to explore their creation’s potential. The panel featured seven of the eight authors of the seminal “Attention Is All You Need Paper” paper, which introduced transformers — a type of neural network…

The pharmaceutical industry is at a critical juncture: AI and other technological advances offer unprecedented potential, yet the cost of developing new drugs has ballooned for decades, surpassing $2 billion in recent years with the projected return on investment (ROI) falling to a mere 1.2% in 2022, according to Deloitte. Another dimension of the problem…

In an AI hype-filled biopharma industry, one company is taking a back-to-basics yet supercomputer-powered approach — using Bayesian analysis on massive patient datasets to guide drug discovery. The company crunches trillions of data points per patient. “It’s massive, which is why we use a supercomputer,” said Niven R. Narain, Ph.D., BPGbio CEO. The company has…

Technically, graphics processing and AI hardware powerhouse Nvidia is also a drug discovery company. It may not discover drugs in-house, but it has developed BioNeMo, a comprehensive generative AI platform for drug discovery and Clara, a collection of healthcare frameworks, applications, and tools, including for biopharma. Nvidia partners include Amgen, AstraZeneca, GSK and Insilico Medicine.…

A vision for data-driven drug development in oncology When Peter Carr, principal software architect of Lantern Pharma, stepped into his full-time role in September 2020, the company was on the cusp of a transformation. While AI had been a focus for a number of years, a fresh infusion of cash provided a possibility of expanding…

Drug discovery, traditionally a labor-intensive process, often involves extensive computational work during experimental screening. Advances in AI, however, promise to streamline this process. To that end, a team from MIT and Tufts has introduced ConPLex, a computational model that uses large language model techniques, similar to those behind ChatGPT. The model analyzes vast amounts of…

For all of its promise in healthcare and elsewhere, deploying artificial intelligence is frequently a challenging endeavor. “Close collaboration between data science teams, other project team members and stakeholders is essential,” said Jennifer Bradford, director of data science at Phastar, the London-headquartered contract research organization. While input from computational, statistical or medical experts could be…