Kathy Fernando, the senior vice president, head of Pfizer Ignite and Pfizer CentreOne, has had a professional trajectory marked by pivotal serendipities. One occurred when attending a seminar at the University of Pennsylvania, where she met Dr. Drew Weissman, a prominent immunologist and RNA vaccine researcher. Weissman, along with Katalin Karikó, recently received the Nobel…
Novo Nordisk stops once-weekly semaglutide kidney outcomes trial early following interim analysis
Novo Nordisk will halt the phase 3b FLOW trial, which investigated the effects of once-weekly injectable semaglutide on kidney outcomes in individuals with type 2 diabetes (T2D) and chronic kidney disease (CKD). The company reached the decision following the recommendation of the independent Data Monitoring Committee (DMC), following an interim analysis that met pre-specified criteria…
Anti-obesity drugs to command a $44 billion market by 2030
As obesity rates continue to soar across the globe, analysts anticipate that the market for anti-obesity drugs will skyrocket in the coming years. Goldman Sachs projects the market to be worth $44 billion by 2030. That’s an almost 16-fold expansion from its valuation of approximately $2.82 billion in 2022. Barclays is even more upbeat on…
Interactive snapshot: 30 promising biotech startups
2023 is shaping up to be a pivotal year for promising biotech startups. While the sector faced multiple waves of layoffs, a silver lining is evident: the growing maturity of AI and genomics technologies is fueling a new wave of startup advances, especially in drug development. Amidst the backdrop of that turbulence, a select group…
Landscape overview: Moderna and Pfizer lead the race in mRNA flu vaccines, with plans for regulatory filings in 2024-2025
mRNA technology helped propel the development of some of the most successful drugs in pharma history — notably, the Comirnaty COVID-19 from Pfizer/BioNTech generated almost $56 billion in 2022 while Moderna’s Spikevax vaccine raked in $18.4 billion. But demand for COVID-19 vaccines continues to cool. In 2023, Comirnaty brought in $15 billion between its two…