Last week, Google DeepMind launched AlphaFold 3, a significant update to its predecessor, AlphaFold 2. The latter has profoundly influenced structural biology and biomedicine in recent years while also attracting some skepticism. While AlphaFold 2 could accurately predict the structures of vast swathes of proteins, AlphaFold 3 ups the ante. It offers higher accuracy and…
Big Pharma clicks soared, but new cell therapies made you buzz: What drove biopharma interest in 2023?
Despite biopharma’s 2023 layoffs and challenges, innovation won your clicks last year with over 130,000 of them on our Pharma 50 report alone. But while giants dominated, your clicks showed disruptive tech wasn’t far behind. The next-most popular article was a roundup of 100 trailblazing cell and gene therapy companies with more than 80,000 views.…
A J&J veteran highlights listening to address overlooked maternal-fetal needs
With nearly 20 years of experience at Johnson & Johnson, Cynthia Accuosti Jones now spearheads the company’s pioneering maternal-fetal medicine group tackling unmet needs in high-risk pregnancies. As vice president of global commercial strategy for autoantibody and maternal fetal health, she spotlights listening as the driver for patient impact. “You can’t have empathy if you…
Unlocking generative AI requires reshaping culture, operations, and talent dynamics
In drug discovery and development, generative AI and natural-language processing (NLP) tools promise more than incremental productivity gains. For companies that can integrate such tools strategically into their workflows, the tools open the door to a fundamental rethinking of operational processes. For instance, generative AI tools can accelerate drafting of research articles, novel target identification,…
Gate Neurosciences takes on depression with event-driven pharmacology
Much of the world is grappling with a mental health crisis — with soaring rates of depression and anxiety. Last year, the startup Gate Neurosciences emerged with a novel approach. While the Carmel, Indiana–based company is focused on synaptic plasticity like many other contemporary CNS companies, it diverges in its strategy. Rather than using a…