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SPR Sensor Chip

By Drug Discovery Trends Editor | March 16, 2010

biacoreGE Healthcare announces the launch of Sensor Chip CM7. Designed for use with GE Healthcare’s Biacore systems, Sensor Chip CM7 has the high immobilization capacity required to support fragment-based screening of small molecules.

Sensor Chip CM7 offers improved screening data quality as it delivers high signal-to-noise ratios. In addition, Sensor Chip CM7 gives improved detection in cases where immobilization levels are unfavorable, such as low concentration of target protein or a target protein that is sensitive to optimal immobilization conditions.

Sensor Chip CM7 has a carboxymethylated dextran matrix covalently attached to gold film, with a higher degree of carboxylation and a denser matrix compared to Sensor Chip CM5. It is capable of binding proteins, nucleic acids, carbohydrates, or small molecules to carboxyl groups on the sensor surface via –NH2, -SH, -CHO, -OH, or -COOH. The analyte is then passed over the surface and any binding is detected by the Biacore system.

GE Healthcare


Filed Under: Drug Discovery

 

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