Sphere Fluidics (Cambridge, U.K.) and Peak Analysis and Automation (Farnborough, U.K.) have launched a new product as they seek to further streamline single-cell analysis in biopharmaceutical workflows.
The companies yesterday announced they have integrated Sphere Fluidics’ Cyto-Mine single-cell analysis system with PAA’s automated plate handler, S-LAB.
Automated micro-plate handling minimizes hands-on involvement and saves time in antibody discovery and cell line development, according to Sphere Fluidics and PAA. Said the companies: “By replacing manual barcode scanning of multi-well microtiter plates and plate loading in the final picodroplet dispensing phase of the Cyto-Mine, the integration of S-LAB increases user flexibility, overall throughput and efficiency.”
The integrated system combines single-cell screening, sorting, imaging, isolation and clone verification. It’s able to process up to 40 million heterogenous mammalian cells in a few hours, according to the companies. The small footprint of the system enables its use in a cell culture hood, which, combined with the de-lidding capability of S-LAB, ensures that processed cells remain sterile.
Sphere Fluidics and PAA first announced their collaboration in January 2019.