High performance liquid chromatography (HPLC) has been and continues to be a workhorse of the pharmaceutical laboratory. Throughout the product life cycle from pre-formulation to quality control, HPLC coupled to dissolution and content uniformity/assay testing are some of the biggest sample sources for HPLC analysis. Sotax, the leader in automated solutions for dissolution testing and automated sample prep has developed a variety of “off-line” autosampler solutions over the decades. “Off-line” samples are withdrawn from instruments, immediately filtered, and collected in a variety of formats. To further automate the analytical workflow and to avoid costly manual transfer mistakes, Sotax has announced the an addition to their line of autosamplers: the SAM sample manager.
The SAM guarantees a seamless flow from dissolution samples to analytical results. Totally flexible and scalable, the system is available in three different capacities to connect to semi-automated single, double, and fully-automated systems: SAM S (small; for up to 240 samples), SAM M (medium; for up to 480 samples), and SAM L (large; for up to 720 samples). The SAM acts as a transfer platform keeping samples protected and injecting them one by one into HPLC, all without any vial transfer. The system works with any HPLC instrument with ready signal functionality and can be integrated with a variety of different injection valves. SAM is driven by the WinSOTAXplus advanced dissolution software while the LC data is processed with the existing chromatography software. SAM will take care of the samples seamlessly from start, to analytical finish.
Filed Under: Drug Discovery