Applied Biosystems Inc. is developing a sequencing-based molecular tool for the genomic analysis of whole transcriptomes. This technology provides detailed characterization of expressed protein-encoding genes, identifies many non-coding RNAs, and includes sample multiplexing capability. This offering will expand the company’s RNA expression analysis solutions portfolio for use with its SOLiD System.
The SOLiD Whole Transcriptome Expression Kit is expected to provide researchers greater insight into biological pathways and molecular mechanisms that regulate cell fate decision, development, and disease progression. The kit is designed to provide new views of a cell’s transcriptome, such as expression of non-coding RNAs, identification of alternative splicing events, expressed SNPs (single nucleotide polymorphisms) or mutations, or translocations and fusion transcripts. The application of the kit should advance treatment of complex diseases, such as diabetes, heart disease, and cancer, and accelerate time course studies in which analysis of differential RNA expression provides insight into the level and mechanism of action of a particular treatment.
This article was published in Drug Discovery & Development magazine: Vol. 10, No. 9, September, 2008, pp. 8.
Filed Under: Genomics/Proteomics