Diagnostic products maker Qiagen will develop a test that detects a genetic mutation targeted by Clovis Oncology’s cancer drug CO-1686, the companies said.
Clovis’ experimental drug CO-1686 is designed to target two different genetic mutations in lung cancer. One mutation causes the cancer, and the other causes resistance to treatment with drugs like Tarceva and Iressa. Clovis expects to start using the Qiagen tests in expansion studies of CO-1686 that will begin later this year.
Clovis Oncology Inc. says CO-1686 could be used as a primary treatment or a secondary treatment for non-small cell lung cancer and as a secondary treatment in patients who are no longer being helped by their initial therapy. Clovis will continue development of its drug and Qiagen will be responsible for development of the test.
The companies did not disclose terms of the collaboration.
The Boulder, Colo., company’s most advanced products include CO-1686 and breast and ovarian cancer drug rucaparib.
Date: October 21, 2013
Source: Associated Press
Filed Under: Drug Discovery