Biotage’s new Isolera compact FLASH purification system enables chemists to easily achieve better separations in shorter purification run-times, while new features result in maximum purity and yield. The Isolera system from Biotage contains intelligent features that allow users to maximize time and resources. The advanced TLC-to-gradient feature automatically creates elution gradients and suggests cartridge and sample size. Compounds can be collected on two separate wavelengths using a variable wavelength detector option. With the Isolera FLASH purification system, up to four solvents can be used in a single gradient to easily purify samples with diverse polarity. A third co-solvent can be isocratically pumped into the binary gradient, maintaining compound solubility and eliminating the over-pressure issues that can be caused by precipitating compounds.
This article was published in Drug Discovery & Development magazine: Vol. 11, No. 6, June, 2008, pp. 8.
Filed Under: Drug Discovery