OncoImmune’s CD24Fc is a first-in-class recombinant fusion protein that targets the innate immune system. OncoImmune recently announced positive top-line findings from an interim efficacy analysis of a Phase 3 study evaluating CD24Fc in people with severe cases of the novel coronavirus. Interim analysis of data from 203 participants showed a 60% higher probability of improvement in clinical status, as defined by the protocol, compared to placebo — with a more than 50% reduction in risk of death or respiratory failure.
“Meaningful new therapeutic options are desperately needed for possibly millions of people around the world who will develop severe or critical COVID-19 disease,” said Dr. Roger M. Perlmutter, president Merck Research Laboratories.
“Recent clinical investigations support the view that CD24Fc may provide benefit beyond standard of care therapy for COVID-19 patients requiring oxygen support, and hence will represent an important addition to the Merck pipeline of investigational medicines and vaccines designed to address the COVID-19 pandemic,” Perlmutter said in a news release.
Filed Under: Drug Discovery, Infectious Disease