MALDI Spotting - Drug Discovery and Development

Eksigent announces the addition of a NanoLC MALDI Spotting System to its nanoflow chromatography product line. Featuring the new Ekspot spotter, the new system complements the company’s existing offerings for nanospray mass spectrometry (MS) proteomics analysis. Integration of the Ekspot with the NanoLC provides single-point control from the Eksigent software. The powerful new tool enables the analysis of complex protein and peptide samples with MALDI MS.

The Ekspot spotter/fraction collector deposits fractions eluted from the NanoLC onto a MALDI plate, while a built-in pump automatically adds the matrix. High positioning accuracy ensures consistent spotting with maximum resolution. The high-capacity system stores up to sixteen MALDI-targets for high-throughput applications.

By eliminating flow splitting, Eksigent’s proprietary microfluidic technology improves reproducibility and sensitivity and eliminates solvent waste. The NanoLC’s precise microscale flow control runs HPLC gradients at rates as low as 20 nL per minute.
www.eksigent.com

This article was published in Drug Discovery & Development magazine: Vol. 11, No. 1, January, 2008, pp. 26.