Bruker has launched two LC-triple quadrupole (LC-TQ) mass spectrometers, the high-performance EVOQ Qube and the ultra-high sensitivity EVOQ Elite, which are setting standards for analytical performance and quantitative robustness. As with Bruker’s SCION GC-TQ platform, the EVOQ series delivers major advances in robustness, ease of method developments, and productivity.
The EVOQ LC-TQ systems incorporate Bruker’s Advance ultra-high pressure liquid chromatography (UHPLC) systems. In addition, the EVOQ platform features several major innovations:
• The industry’s first vacuum-insulated probe (VIP) heated electrospray technology preserves and ionizes thermally fragile molecules with outstanding sensitivity.
• The Active Exhaust atmospheric pressure ionization source with a robust orifice vacuum interface significantly enhances quantitative robustness for difficult samples.
• The ‘flat-tuning’ Interlaced Quadrupole Dual Funnel (IQ-DF) maximizes sensitivity.
• PACER software enables ‘exception based data-review’, a revolutionary feature that significantly reduces the error rate for quantitative analysis.
Bruker’s lens-free triple-quad mass filter design, which enhances MRM performance, is standard on all EVOQ systems, making the EVOQ LC-TQ inherently easier to use and maintain. Other high-performance TQ features include Bruker’s unique Compound Based Scanning (CBS) technology, the novel VIP heated-ESI and APCI ion sources, fast 14,000 amu/sec scan speed and 25 milliseconds positive/negative ion switching, all for leading-edge TQ performance and analytical power.
Filed Under: Drug Discovery
