Mallinckrodt Baker’s J.T.Baker ULTRA Liquid Chromatography/Mass Spectrometry (LC/MS) solvents are designed for the most demanding ultra-high pressure liquid chromatography (UHPLC) and mass spectrometry research and analytical testing applications, such as proteomics, drug discovery, pharmacokinetics and clinical research.
Through a combination of process and packaging enhancements, the ULTRA LC/MS solvents are intended to deliver enhanced instrument performance and extend the useful life of UHPLC columns by controlling trace metal impurities, organic impurities and particle levels. The solvents are filtered through 0.1 micrometer filters which provide extremely low particle counts, and are packaged in 1 L borosilicate bottles that minimize leaching of trace metal impurities. Enhanced suitability testing is performed to ensure that key organic impurities, such as polyethylene glycol (PEG) and phthalates, are controlled throughout the manufacturing and packaging processes.
“As the use of advanced instrumentation in the most demanding research and analytical testing applications grows, the need for ultra high-purity solvents has increased. Low-level chemical impurities can cause metal adduct formation which can lead to erroneous peaks,” said Russell Thorpe, global marketing director, Mallinckrodt Baker. “Our J.T.Baker ULTRA LC/MS solvents have been designed to meet strict quality requirements, which optimize UHPLC instrument performance and reduce the need for costly rework.”
This product was featured in Drug Discovery & Development magazine: Vol. 13, No. 3, April 2010, p. 8.
Filed Under: Drug Discovery