Ionis Pharmaceuticals, Inc. has licensed IONIS-AZ5-2.5Rx (AZD2373) to AstraZeneca. IONIS-AZ5-2.5Rx is a Generation 2.5 antisense drug, discovered by Ionis and designed to inhibit an undisclosed target to treat a genetically associated form of kidney disease. AstraZeneca will be responsible for developing and commercializing IONIS-AZ5-2.5Rx.
“This is the second drug to enter development under our strategic collaboration with AstraZeneca in cardiovascular, metabolic, and renal diseases,” said Brett P. Monia, Ph.D., chief operating officer and senior vice president of antisense drug discovery and translational medicine at Ionis.
Ionis will receive a $30 million upfront payment from AstraZeneca for IONIS-AZ5-2.5Rx and may also receive up to $300 million in additional development and regulatory milestone payments and tiered, low double-digit royalties from sales of the potential new medicine.
(Source: Ionis Pharmaceuticals, Inc.)
Filed Under: Drug Discovery