CRi announced an imaging system for live mice that provides autofluorescence removal from images. The CRi Maestro EX In-Vivo Imaging System uses the firm’s patented FLEX technology, which allows broad- or narrow-bandwidth (±10-20 nm) imaging to permit greater throughput and increased multiplexing. Featuring spectral unmixing software tools and a configurable imaging area, this system can acquire multispectral images in seconds, image any fluorophore which emits beyond 500 nm, and is up to 300 times more sensitive than monochrome, according to the company.
Equipped with a light-tight chamber, Xenon-based illuminator, and liquid crystal tunable multispectral camera, the CRi Maestro EX In-Vivo Imaging System incorporates proprietary algorithms that yield images reflecting the true abundance of each marker isolated from others. This allows quantitating more markers accurately, resolving overlapping emission signals, including autofluorescence and allows longitudinal studies on one animal.
The CRi Maestro EX In-Vivo Imaging System is available with an optional heated stage, anesthesia kit, and an all-optical Dynamic Contrast Enhancement (DyCE) tool that generates anatomic organ maps.
Filed Under: Drug Discovery