Molecular Devices have announced the release of their MetaMorph Super-Resolution System with synchronized image acquisition and processing, enabling analysis of object details smaller than 250 nanometers in fixed and live cells. The new system features real-time image processing with its GPU accelerated hardware, expanding the capabilities of optical microscopy in research and supports numerous scientific applications, from time-lapse studies to 3-D investigations.
Using light microscopy alone, images of biological matter smaller than 250 nanometers appear blurred and, as a result, are virtually impossible to analyse. Super-resolution microscopy can help to overcome the limits of light microscopy by reconstructing images at a resolution surpassing the diffraction limit of the objective lens. With patent-pending image processing techniques, the new MetaMorph Super-Resolution System is capable of 20 nm lateral resolution in real-time.
The new system is exclusively licensed from the Center for Scientific Research and University of Bordeaux in France, and builds on the powerful and flexible MetaMorph Software. The user-friendly software guides researchers through setup, acquisition, and analysis, with a dedicated workspace in the user interface ensuring that relevant configuration and display settings are readily accessible. Side-by-side displays and image statistics provide a multifaceted view of the quality and progress of image acquisition and processing. For added flexibility, a unique hardware acceleration component supports fast acquisition and analysis with real-time super-resolution image display. An optional “offline” mode allows super-resolution processing of previously acquired images. The system is compatible with most fluorescence and TIRF microscopes.
Filed Under: Drug Discovery