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Hookipa Pharma announces oncology partnership with Merck

By Brian Buntz | September 15, 2021

HookipaImmunotherapy-specialist Hookipa Pharma (NSDQ:HOOK) has announced a clinical collaboration and supply agreement with Merck (NYSE:MRK). Hookipa will test its immunotherapeutic HB-200 in conjunction with Merck’s blockbuster anti-PD-1 therapy, Keytruda (pembrolizumab), as first-line treatment for patients with advanced head and neck squamous cell carcinoma (HNSCC).

Last year, Merck raked in $14.5 billion in sales revenue from Keytruda.

“There remains considerable unmet treatment need for people with metastatic head and neck cancers, and we believe the combination of HB-200 and Keytruda may offer hope,” said Joern Aldag, Hookipa CEO, in a statement.

Hookipa reports that the company has seen early success with combining Keytruda and HB-200 in heavily pre-treated patients.

The company plans on launching a Phase 2 trialing the combination of HB-200 with Keytruda in 2022.

The company is developing a range of novel arenaviral immunotherapies for oncology and infectious diseases.

After announcing the Merck collaboration, HOOK shares ticked up 1.37% apiece to $6.30.


Filed Under: Oncology
Tagged With: cancers, HB-200, head and neck squamous cell carcinoma, HNSCC, Hookipa Pharma, Keytruda, Merck, oncology, pembrolizumab
 

About The Author

Brian Buntz

As the pharma and biotech editor at WTWH Media, Brian has almost two decades of experience in B2B media, with a focus on healthcare and technology. While he has long maintained a keen interest in AI, more recently Brian has made making data analysis a central focus, and is exploring tools ranging from NLP and clustering to predictive analytics.

Throughout his 18-year tenure, Brian has covered an array of life science topics, including clinical trials, medical devices, and drug discovery and development. Prior to WTWH, he held the title of content director at Informa, where he focused on topics such as connected devices, cybersecurity, AI and Industry 4.0. A dedicated decade at UBM saw Brian providing in-depth coverage of the medical device sector. Engage with Brian on LinkedIn or drop him an email at [email protected].

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