Drug Discovery and Development

  • Home Drug Discovery and Development
  • Drug Discovery
  • Women in Pharma and Biotech
  • Oncology
  • Neurological Disease
  • Infectious Disease
  • Resources
    • Video features
    • Podcast
    • Webinars
  • Pharma 50
    • 2025 Pharma 50
    • 2024 Pharma 50
    • 2023 Pharma 50
    • 2022 Pharma 50
    • 2021 Pharma 50
  • Advertise
  • SUBSCRIBE

High-Throughput Screener

By Drug Discovery Trends Editor | November 2, 2009

CellKeyThe CellKey 384 System from MDS Analytical Technologies is a high-throughput 384-well instrument that utilizes the award-winning, label-free, cellular-measurement technology of the original 96-well CellKey  System. The system’s four-fold increase in throughput enables researchers to accelerate the screening of endogenous targets and reduce the cost-per-well by using less cells and reagents.

The CellKey 384 System was created to enable label-free, real-time analysis of cell-surface receptor activity in a single comprehensive assay format independent of the signaling pathway. Researchers can now perform primary screens on larger libraries since the 384-well format is more conducive to high-throughput screening environments than previous 96-well systems which targeted therapeutic and secondary screening. The system is used to accelerate the development of drug therapies for inflammation, oncology, and cardiovascular disease. The label-free feature removes the time-consuming and often costly step of trying to optimize the assays using tags or dyes.

With an integrated onboard fluidics head, the CellKey 384 System enables compound dispensing to all 384 wells, while simultaneously measuring the kinetic cellular responses. Additionally, an incorporated tip wash system extends unattended throughput during automation, and reduces costs related to pipette tip consumables.

MDS Analytical Technologies

 


Filed Under: Drug Discovery

 

Related Articles Read More >

Lokavant’s Spectrum v15 uses AI to cut trial-feasibility modeling from weeks to minutes
Prime time for peptide-based drug discovery 
Why smaller, simpler molecular glues are gaining attention in drug discovery
Glass vial, pipette and woman scientist in laboratory for medical study, research or experiment. Test tube, dropper and professional female person with chemical liquid for pharmaceutical innovation
Unlocking ‘bench-to-bedside’ discoveries requires better data sharing and collaboration
“ddd
EXPAND YOUR KNOWLEDGE AND STAY CONNECTED
Get the latest news and trends happening now in the drug discovery and development industry.

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.
Drug Discovery and Development
  • MassDevice
  • DeviceTalks
  • Medtech100 Index
  • Medical Design Sourcing
  • Medical Design & Outsourcing
  • Medical Tubing + Extrusion
  • Subscribe to our E-Newsletter
  • Contact Us
  • About Us
  • R&D World
  • Drug Delivery Business News
  • Pharmaceutical Processing World

Copyright © 2025 WTWH Media LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media
Privacy Policy | Advertising | About Us

Search Drug Discovery & Development

  • Home Drug Discovery and Development
  • Drug Discovery
  • Women in Pharma and Biotech
  • Oncology
  • Neurological Disease
  • Infectious Disease
  • Resources
    • Video features
    • Podcast
    • Webinars
  • Pharma 50
    • 2025 Pharma 50
    • 2024 Pharma 50
    • 2023 Pharma 50
    • 2022 Pharma 50
    • 2021 Pharma 50
  • Advertise
  • SUBSCRIBE