FEI Company released a set of software applications that increase the throughput and ease-of-use of its electron microscopes for biological research. The four software packages make electron microscopes more useful for life science researchers involved in structural, cellular, and tissue biology as they build the full solution from sample to biological answer.
The software includes the Correlative Navigation Utility for the correlation of navigational coordinate systems between different types of microscopes, such as optical and electron microscopes.. EPU is an automated data collection procedure that facilitates the acquisition of large data sets (from thousands or tens of thousands of nominally identical particles) used to reconstruct high resolution 3D models with the single particle analysis technique.
ARGOS (Automated Recognition of Geometries, Objects, and Segmentations) is a 3D template fitting capability that helps to localize macromolecules in their native cellular context and relate orientation properties of these molecules to their environment.
Extended Slice & View is a 3D reconstruction technique that combines automated serial cross sectional SEM image acquisition into a virtual 3D volume image of the tissue or cell. The images may be stitched together from multiple images of the section surface to retain nanometer scale detail over many micrometer fields of view.
Filed Under: Drug Discovery