DNA2.0, a leading bioengineering solutions provider, announced a partnership with Aldevron to improve recombinant protein production in insect cell culture. By pairing DNA2.0‘s GeneGPS technology with Aldevron’s protein production experience, the two companies will develop enhanced gene synthesis algorithms for baculovirus protein expression in insect cells.
“Aldevron’s expertise in protein expression and production compliments DNA2.0’s gene design and expression optimization technology,” said Tom Foti, Vice President of Aldevron. “Through this collaboration, we will be able to provide our clients an improved method for producing high quality proteins with increased yields—all while saving them crucial time and money.”
Insect cell expression systems are valued for high expression levels that permit folding, oligomerization and other post-translational modifications in manners that are often identical to those that occur in mammalian cells. By increasing the productivity from insect cell culture, the collaboration between Aldevron and DNA2.0 will further benefit drug discovery research and commercial therapeutic protein production.
“We have successfully optimized expression for a variety of hosts, including bacteria, yeast, fungus, plant, and mammalian, and we are excited to team with Aldevron to extend our expertise to baculovirus expression in insect cells,” said Jeremy Minshull, PhD, cofounder and CEO of DNA2.0. “By combining our patented GeneGPS technology—which has been proven to increase protein expression up to 100-fold—with Aldevron’s strength in large scale protein production, I’m confident that we will develop a best-in-class solution for insect cell culture.”
Date: August 30, 2012
Filed Under: Drug Discovery