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DNA, RNA, and Protein Separation

By Drug Discovery Trends Editor | July 21, 2008

Caliper Life Sciences LabChip GX11Caliper Life Sciences, Inc. introduced two microfluidics-based separations products, the LabChip GX and LabChip GXII benchtop systems, for fast, automated, 1-D electrophoretic separations of protein, DNA, and RNA samples. The LabChip GX represents a low price entry system targeted at genomics applications, while the GXII combines both genomics and protein research applications.

The LabChip GX series of instruments will be marketed by Caliper and is designed to provide scientists novel benefits including extended walk away time, higher throughput and economical plate processing ability. Caliper also provides solutions to scientists with lower throughput needs through its collaborations with Agilent and Bio-Rad.

Both systems combine Caliper’s reproducible assay technology with advanced data analysis and visualization software, and 96-well and 384-well plate compatibility.

Users can analyze samples in seconds instead of minutes, according to Caliper. The data management software suite included with each system allows users to visualize results via an electropherogram or virtual gel view. It also provides data in tabular form, which can then be analyzed or exported into a spreadsheet format.

The new LabChip GX instrument has been designed for the analysis of RNA integrity for better RT-PCR and microarray gene expression data, DNA fragment analysis for sequencing applications and genotyping transgenic mice, and numerous other applications that require accurate size, concentration, or purity analysis of nucleic acid samples. The LabChip GX can analyze any single sample, or a subset of samples in a microtiter plate using an intuitive GUI interface. This feature enables researchers to assess RNA integrity by randomly sampling a plate or conduct “hit picking” experiments on samples of particular interest.

The LabChip GXII system, which is a functional replacement of the LabChip 90.

Caliper Life Sciences

See this product at Drug Discovery & Development of Innovative Therapeutics World Congress, Booth 638. 


Filed Under: Drug Discovery

 

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