Endra Life Sciences announced the launch of the Nexus 128, a preclinical photoacoustic computed tomography (CT) scanner for small animal imaging. The system is used for simple, fast, non-invasive quantification of tumor vasculature and other physiological parameters for preclinical research. The scanner makes in vivo quantification of tumor vasculature possible without the need for contrast agents and helps preclinical researchers gain deeper insight into areas such as how drugs treat disease and cancer progression, without ionizing radiation or complicated equipment.
The name Nexus 128 represents the convergence of light and sound in a powerful new imaging approach. It employs a detector array consisting of 128 individual acoustic receiver elements arranged in a patented geometry. The system generates multispectral, quantitative, three dimensional images of tumor vasculature and hemoglobin concentration in under 2 minutes, and completes volumetric anatomical scans in as little as 12 seconds.
Photoacoustic imaging is a process using short pulses of light absorbed deep within tissue create sound waves that are detected by ultrasound receivers to create an image. This non-invasive approach provides high contrast imaging at depths, and spatial resolution far exceeding existing optical techniques. Recent advances in pulsed laser sources, ultrasound devices, and image reconstruction algorithms have enabled the photoacoustic effect to be applied to biological imaging.
Filed Under: Drug Discovery