11,000 people are predicted to die from acute myeloid leukemia (AML) in 2019, according to the American Cancer Society. The cancer starts in the bone marrow. There, mutated genes fail to prevent blood cells from replicating again and again and again, growing tumors. Chemotherapy helps two out of three patients achieve remission. And recently, drug…
Rare But Important Gene Target Found in Many Tumor Types
A consortium of researchers led by Georgetown Lombardi Comprehensive Cancer Center investigators have completed the largest analysis of a new gene fusion they believe is responsible for development of a wide spectrum of cancer types. They say their studies show that errant gene fusions in neuregulin-1 or NRG1, which are present in about 0.2 percent…
Precise Decoding of Breast Cancer Cells Creates New Option for Treatment
Every year more than 1.7 million women all over the world are diagnosed with breast cancer, with the disease ending fatally for around half a million patients. In the fight against breast cancer, research is being done into novel therapeutic approaches that are designed to target cancer cells more precisely and also activate the tumor-associated…
Cancer-killing Combination Therapies Unveiled with New Drug-screening Tool
Researchers Develop Treatment That Turns Tumors Into Cancer Vaccine Factories
New Hope For Treating Childhood Brain Cancer
There could be new treatments on the horizon for diffuse intrinsic pontine glioma, or DIPG, a devastating form of brain cancer that afflicts young children and is currently incurable. Recent experiments in animal models of the disease have identified an experimental drug that effectively destroys DIPG cells. And a team of Rockefeller scientists just figured…
Gut Microbiome Directs the Immune System to Fight Cancer
Preventative Cancer Vaccine Shows Promise for High-Risk Patients
Data From Two KEYNOTE Trials Show Pembrolizumab Benefited Patients With Advanced Small Cell Lung Cancer
Single Agent Umbralisib Effective for Relapsed Slow-Growing Lymphoma
Glowing Tumors Show Scientists Where Cancer Drugs Are Working
Experimenting with mice, Johns Hopkins researchers report they have successfully used positron emission tomography (PET) scans to calculate in real time how much of an immunotherapy drug reaches a tumor and what parts of a cancer remain unaffected. The technique uses PET imaging of a synthesized radiolabeled protein that locks on to tumor cells, letting…
Tumor-associated Immune Cells Hinder Frontline Chemotherapy Drug in Pancreatic Cancer
Topical Immunotherapy Keeps Skin Cancer Risk at Bay
New Class of Drugs Could Treat Ovarian Cancer
Key to Common Cancer Pathway Discovered
The Story of GARP: A Potential Target For Cancer Immunotherapy
Targeting Stem-like Cells Could Prevent Ovarian Cancer Recurrence
When a Cell’s ‘Fingerprint’ Can Be a Weapon Against Cancer
New ‘Tracers’ Improve Diagnosis of Cancer and may be Useful for Treatment
Researchers have identified two new nuclear medicine tracers that make it easier to diagnose and potentially treat cancer. A proof-of-concept investigation, published in the March issue of The Journal of Nuclear Medicine, reports that 68Ga-FAPI positron emission tomography/computed tomography (PET/CT) provides high-contrast images with quality equal to or better than that of the standard 18F-FDG…
Seawater Bacteria Provides Leads to Fight Melanoma
Genomics Could Better Match Treatments to Pancreatic Cancer Patients
Tool Reveals Molecular Causes of Disease, Including Infant Cancer
Princeton University researchers are gaining new insights into the causes and characteristics of diseases by harnessing machine learning to analyze molecular patterns across hundreds of diseases simultaneously. Demonstrating a new tool now available to researchers worldwide, the team of computer scientists and biologists has already uncovered and experimentally confirmed previously unknown contributions of four genes…
