Drug Discovery and Development

  • Home Drug Discovery and Development
  • Drug Discovery
  • Women in Pharma and Biotech
  • Oncology
  • Neurological Disease
  • Infectious Disease
  • Resources
    • Video features
    • Podcast
    • Voices
    • Webinars
  • Pharma 50
    • 2025 Pharma 50
    • 2024 Pharma 50
    • 2023 Pharma 50
    • 2022 Pharma 50
    • 2021 Pharma 50
  • Advertise
  • SUBSCRIBE

Big Gain Seen for Non-Small Cell Lung Cancer Market

By GlobalData | November 23, 2016

Non-small cell lung cancer market to gain over $20 billion in value by 2025, says GlobalData.

The non-small cell lung cancer (NSCLC) market across the eight major markets of the U.S., France, Germany, Italy, Spain, the U.K., Japan, and China, is set to rise from $6.21 billion in 2015 to $26.71 billion by 2025, representing a very strong compound annual growth rate of 15.7%, according to research and consulting firm GlobalData.

The company’s latest report states that the impressive strength of the market over the next decade can be attributed to the increasing incorporation of premium-priced immune checkpoint inhibitors into the NSCLC treatment algorithm, the launch of new targeted therapies, and the rising incidence of the disease across the eight major markets.

Cai Xuan, Ph.D., GlobalData’s analyst covering oncology, explains: “In 2015, the NSCLC space was largely dominated by generic chemotherapy and targeted therapies, which accounted for around 94% of the market, while immuno-oncology sales accounted for just 6%. In 2025, that trend will be reversed, with 65% of the total NSCLC market going to immuno-oncology therapies, and the remaining 35% being split between chemotherapy and targeted agents.

“A major trend in corporate strategy is the pairing of programmed cell death protein 1 (PD-1) checkpoint inhibitors with other agents. In the crowded PD-1 space, as drugs with identical mechanisms of action are launched, players are looking for ways to boost efficacy in hopes of differentiating their product from that of their competitors.”

Companies such as Merck, Roche, and Bristol-Myers Squibb are evaluating their PD-1 checkpoint inhibitors in combination with chemotherapies, targeted agents, and/or other immuno-oncology products.

In the targeted therapy arena, companies are developing novel therapies for previously unactionable mutations to address high unmet need in specific patient populations. For example, Kirsten rat sarcoma virus (KRAS)-mutant NSCLC makes up a significant (25–30%) share of the total NSCLC patient pool, yet there are no targeted therapies currently marketed for this segment of the population.

Xuan notes: “Eli Lilly’s pipeline agent abemaciclib targets KRAS patients, yet its lack of efficacy is expected to severely limit its uptake, leaving opportunities for other KRAS targeted therapies to enter the space.

“In addition to novel therapies, companies are also developing second- and third-generation targeted therapies to provide better options for patients with actionable mutations. GlobalData expects these next-generation targeted therapies to take significant patient share away from their predecessors.”

GlobalData is a global research and consulting firm offering advanced analytics.

(Source: GlobalData)


Filed Under: Drug Discovery

 

Related Articles Read More >

EVEREST lead investigator on why Dupixent sets a new bar for treating coexisting CRSwNP and asthma
Sanders, King target DTC pharma ads but the industry worries more about threats to its $2B R&D model
Zoliflodacin wins FDA nod for treatment of gonorrhea
FDA approved ENFLONSIA for the prevention of RSV in Infants
“ddd
EXPAND YOUR KNOWLEDGE AND STAY CONNECTED
Get the latest news and trends happening now in the drug discovery and development industry.

MEDTECH 100 INDEX

Medtech 100 logo
Market Summary > Current Price
The MedTech 100 is a financial index calculated using the BIG100 companies covered in Medical Design and Outsourcing.
Drug Discovery and Development
  • MassDevice
  • DeviceTalks
  • Medtech100 Index
  • Medical Design Sourcing
  • Medical Design & Outsourcing
  • Medical Tubing + Extrusion
  • Subscribe to our E-Newsletter
  • Contact Us
  • About Us
  • R&D World
  • Drug Delivery Business News
  • Pharmaceutical Processing World

Copyright © 2025 WTWH Media LLC. All Rights Reserved. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of WTWH Media
Privacy Policy | Advertising | About Us

Search Drug Discovery & Development

  • Home Drug Discovery and Development
  • Drug Discovery
  • Women in Pharma and Biotech
  • Oncology
  • Neurological Disease
  • Infectious Disease
  • Resources
    • Video features
    • Podcast
    • Voices
    • Webinars
  • Pharma 50
    • 2025 Pharma 50
    • 2024 Pharma 50
    • 2023 Pharma 50
    • 2022 Pharma 50
    • 2021 Pharma 50
  • Advertise
  • SUBSCRIBE