It remains mysterious why humans get infected by some bacterial or viral pathogens relatively easily while animals that have very similar tissues and immune functions do not. This chasm also is the reason why researchers frequently face problems in their efforts to model pathogenic diseases in animal models, such as mice, and why drugs developed…
Driving Drug Resistance Out of Fungi
Candida albicans is a notorious human fungal pathogen that causes thrush and serious systemic infections. Opportunistic C. albicans fungi, which often live inconspicuously in the normal flora of human skin and gut, can switch from their harmless stealth mode to become aggressive pathogens, especially in people whose immune systems are already compromised by pre-existing diseases…