A discovery about how human cells are ‘triggered’ to undergo an inflammatory type of cell death could have implications for treating cancer, stroke and tissue injury, and immune disorders. A research team from the Walter and Eliza Hall Institute in Melbourne identified the molecular trigger in human cells that drives necroptosis, and implicated defects in…
Structure of Protein Pair Provides Blueprint For Future Drugs
Atomic Map Gives Malaria Drug New Lease on Life
Researchers have for the first time mapped how one of the longest-serving malaria drugs works, opening the possibility of altering its structure to make it more effective and combat increasing malaria drug resistance. The study produced a precise atomic map of the frontline antimalarial drug mefloquine, showing how its structure could be tweaked to make…
New Compound Shows Promise in Treating Multiple Cancers
Snail Venom Holds Key to Better Diabetes Treatments?
New research has found that venom extracted from a species of marine cone snail could hold the key to developing ‘ultra-fast-acting’ insulins, leading to more efficient therapies for diabetes management. Researchers from Australia and the US have successfully determined the three-dimensional structure of a cone snail venom insulin, revealing how these highly efficient natural proteins…