For the first time, scientists have visualized the interaction between two critical components of the body’s vast cellular communication network, a discovery that could lead to more effective medications with fewer side effects for conditions ranging from migraine to cancer. The near-atomic resolution images, published today in Nature, show a G-protein coupled receptor (GPCR) called rhodopsin bound to…
Diabetes Drug May Slow Parkinson’s Disease Progression
A new investigational drug originally developed for type 2 diabetes is being readied for human clinical trials in search of the world’s first treatment to impede the progression of Parkinson’s disease following publication of research findings this week in the journal Science Translational Medicine. “We hope this will be a watershed moment for millions of people living with…
New Computational Tool May Speed Drug Discovery
A new computational tool called fABMACS is helping scientists see beyond static images of proteins to more efficiently understand how these molecules function, which could ultimately speed up the drug discovery process. Proteins are the molecular workhorses of biology–they carry out the instructions written in the genetic code. Their shape plays a crucial role in their function…
New Computational Tool May Speed Drug Discovery
A new computational tool called fABMACS is helping scientists see beyond static images of proteins to more efficiently understand how these molecules function, which could ultimately speed up the drug discovery process. Proteins are the molecular workhorses of biology — they carry out the instructions written in the genetic code. Their shape plays a crucial role in their…