Researchers in the University of Wisconsin-Madison Department of Biochemistry have discovered that a cellular pump known to move drugs like antibiotics out of E. coli bacteria has the potential to bring them in as well, opening new lines of research into combating the bacteria. The discovery could rewrite almost 50 years of thinking about how…

University of Wisconsin-Madison engineers have developed methods to observe gene editing in action, and they’re putting those capabilities to work to improve genetic engineering techniques. “Ultimately, the knowledge we gain from this project has the potential to set the foundation for new preclinical platforms in precision medicine,” says Krishanu Saha, an assistant professor of biomedical…

A team of researchers led by Yoshihiro Kawaoka, professor of pathobiological sciences at the University of Wisconsin-Madison School of Veterinary Medicine, has developed technology that could improve the production of vaccines that protect people from influenza B. That technology is an influenza B vaccine virus “backbone” that would allow producers to grow vaccine viruses at…

During the 2014-15 flu season, the poor match between the virus used to make the world’s vaccine stocks and the circulating seasonal virus yielded a vaccine that was less than 20 percent effective. While this year’s vaccine is a much better match to the circulating seasonal strains of influenza, the shifty nature of the virus…