DNA Vaccine Leads to Immune Responses in HPV-related Head and Neck Cancer
A therapeutic vaccine can boost antibodies and T cells, helping them infiltrate tumors and fight off human papillomavirus (HPV)-related head and neck cancer. Researchers from the Abramson Cancer Center of the University of Pennsylvania tested the immunotherapy approach in two groups of patients with advanced head and neck squamous cell carcinoma (HNSCCa) and found 86…
Diabetes Drugs Act as Powerful Curb for Immune Cells in Controlling Inflammation
Trial Shows AZEDRA Can Be Effective, Safe for Treatment of Rare Neurodegenerative Tumors
Bacteria Boost Antifungal Drug Resistance in Severe Childhood Tooth Decay
Personalized Tumor Vaccine Shows Promise in Pilot Trial
Cabozantinib Shows Promise as First Line Treatment for Differentiated Thyroid Cancer
Proton Therapy Lowers Treatment Side Effects in Pediatric Head and Neck Cancer Patients
Pediatric patients with head and neck cancer can be treated with proton beam therapy (PBT) instead of traditional photon radiation, and it will result in similar outcomes with less impact on quality of life. Researchers from the Perelman School of Medicine at the University of Pennsylvania as well as Children’s Hospital of Philadelphia analyzed cases of pediatric head and…
Preclinical Study Outlines Cardiovascular Side-Effects of Breast Cancer Drug
A receptor protein that is the target of the breast cancer drug trastuzumab (Herceptin) is needed for proper heart blood-vessel development, reported researchers from the Perelman School of Medicine at the University of Pennsylvania. They published their findings this month in Nature Communications. These discoveries have implications for better understanding the cardiovascular side effects of…
New CAR T Cell Therapy Using Double Target Aimed at Solid Tumors
New Antiviral Drugs Could Come from DNA ‘Scrunching’
Evidence of DNA “scrunching” may one day lead to a new class of drugs against viruses, according to a research team from the Perelman School of Medicine at the University of Pennsylvania, the Georgia Institute of Technology, and Columbia University. The team is led by Stephen C. Harvey, PhD, an adjunct professor in the department…
