DNA-damaging agents, or “DDAs,” make up the most widely used group of cancer drugs. Yet their therapeutic success has been curtailed by drug resistance—either present in cancer cells from the disease onset or arising during treatment. Now, biologists at the University of California San Diego have discovered a new way of re-sensitizing drug-resistant human tumor…
Machine Learning IDs Antibiotic-resistance Genes in TB-causing Bacteria
Pair of Discoveries Illuminate New Paths to Flu and Anthrax Treatments
Antibiotic Effective Against Drug-Resistant Bacteria in Pediatric Skin Infections
Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial scourge. As its name suggests, MRSA is resistant to most common antibiotics and thus difficult to treat, particularly in children where it commonly causes complicated skin and skin structure infections. In a randomized, controlled clinical trial — the first of its kind — a multi-institution research team reports that daptomycin,…