Discovery of a new feature of a large class of pathogenic viruses may allow development of new antiviral medications for the common cold, polio and other illnesses, according to a new study publishing June 11 in the open-access journal PLOS Biology by Rana Abdelnabi and Johan Neyts of the University of Leuven, Belgium, and James…
How HIV DNA is Blocked from Entering the Cell Nucleus
Advancement May Provide New Treatment for Cutaneous Leishmaniasis
How the Immune System Protects Against Zika-Induced Neurological Symptoms
How Damaging Immune Cells Develop During Tuberculosis
Alcohol Increases Tuberculosis-related Deaths in Young Mice
TB Drug May Work Better Than Others in its Class
Improved Retention, Outcomes With Same-Day HIV Testing and Treatment
New Strategy Identifies Potential Drugs and Targets for Brain Repair
New Technique Could Enable Safer Production of Polio Vaccines
A new method to produce a stable fragment of poliovirus could enable safer production of vaccines, according to a study published in PLOS Pathogens. Polio is almost completely eradicated, but polio vaccines are still needed to protect against the possibility of re-emergence. However, existing vaccine production methods require growing live viruses, which poses safety risks. Previous…
Larger Testing Groups Necessary to Find Effective Malaria Vaccine, Study Suggests
Malaria elimination: Vaccines should be tested on larger groups of volunteers. To find an effective vaccine against malaria it is crucial to test candidate vaccines on larger groups of people than previously thought – according to a new study published in PLOS Computational Biology. The researchers from Erasmus MC Rotterdam and Radboud University Medical Center Nijmegen…
Prescribing Drugs for Cardiovascular Disease Prevention in UK
Broad Range of Prices for HCV Drugs Raises Concerns About Affordability
The prices and affordability of recently developed and highly effective direct-acting antivirals for treating hepatitis C (HCV) vary greatly among countries worldwide, according to a study published this week in PLOS Medicine. Suzanne Hill and colleagues from the World Health Organization undertook an economic analysis of prices for a 12-week course of treatment with sofosbuvir and…